The
Calicivirus
Pages
| The genus Recovirus is
comprised of a single species, Recovirus A. Rhesus enteric calicivirus |
|
| Tulane virus (TV) was
isolated from stool samples of captive juvenile rhesus macaques (Macaca
mulatta) of the Tulane National Primate Research Center (Farkas
et al.,
2008). The complete genome of TV contains 6,714 nucleotides and has
a poly(A) tail. It is organized into three open reading frames that
encode the non-structural polyprotein (ORF1), the capsid protein
(ORF2) a possible minor structural protein (ORF3). TV can be
cultured in a monkey kidney cell line (LLC-MK2) with the appearance
of typical CPE. Tulane virus is most closely related to
St-Valérien-like caliciviruses
and noroviruses. Tulane
virus has been proposed to represent a novel calicivirus genus with
the suggested name "Recovirus" (from Rhesus
Enteric Calicivirus). This virus
has since been found in humans (Smits et al., 2011). References Farkas, T., Sestak, K., Wei, C. and Jiang, X. (2008). Characterization of a rhesus monkey calicivirus representing a new genus of Caliciviridae. J. Virol. 82: 5408-5416. Epub 2008 Apr 2. Farkas, T., Dufour, J., Jiang, X. and Sestak, K. (2010). Detection of norovirus-, sapovirus- and rhesus enteric calicivirus-specific antibodies in captive juvenile macaques. J. Gen. Virol. 91: 734-738. Epub 2009 Nov 4. Farkas, T., Cross, R.W., Hargitt, E. 3rd, Lerche, N.W., Morrow, A.L. and Sestak, K. Genetic diversity and histo-blood group antigen interactions of rhesus enteric caliciviruses. J. Virol. 84: 8617-8625. Epub 2010 Jun 16. Smits, S.L., Rahman, M., Schapendonk, C.M., van Leeuwen, M., Faruque, A.S., Haagmans, B.L., Endtz, H.P. and Osterhaus, A.D. (2011). Calicivirus from novel Recovirus genogroup in human diarrhea, Bangladesh. Emerging Infect. Dis. 18: 1192-1195. Wei, C., Farkas, T., Sestak, K. and Jiang, X. (2008). Recovery of infectious virus by transfection of in vitro-generated RNA from tulane calicivirus cDNA. J. Virol. 82: 11429-11436. Epub 2008 Sep 10. |